Figure 5.

Schematic depiction of salient features of the structural organisation of the radial neuron regulatory glycoprotein reelin (a) and its regulatory protein DAB-1 (Disabled-1) (b) which have guidance roles that control radial neuron growth and orientation signalling through the very low-density lipoprotein receptor (VLDLR) and apolipoprotein E receptor 2 (ApoER2) (c,d). The complexity of ephrin–ephrin receptor signalling showing ephrin receptors and the GPI anchored and transmembrane ephrin signalling combinations (e). Structural representation of the structural organisation of the ephrin receptors (f).