Table 3.
Multivariate Cox regression model of factors predicting the progression-free survival.
| Predictor Variables | Hazard Ratio (HR) | 95% CI of HR | p Value | |
|---|---|---|---|---|
| Lower | Upper | |||
| Gender | ||||
| Male | 1 | |||
| Female | 2.100 | 1.270 | 3.470 | 0.004 |
| ECOG | ||||
| 0 | 1 | |||
| 1/2 | 1.168 | 0.649 | 2.101 | 0.604 |
| 3 | 2.922 | 1.363 | 6.265 | 0.006 |
| Platelet/lymphocyte ratio | ||||
| ≤270 | 1 | |||
| >270 | 1.687 | 1.051 | 2.710 | 0.030 |
| Sarcopenia | ||||
| Yes | 2.333 | 1.251 | 4.349 | 0.008 |
| No | 1 | |||
| Metastatic site | ||||
| Non-liver | 1 | |||
| Liver | 2.241 | 1.369 | 3.671 | 0.001 |
| Sunitinib dose (mg) | ||||
| 25 | 2.205 | 0.809 | 6.008 | 0.122 |
| 37.5 | 2.437 | 1.011 | 5.872 | 0.047 |
| 50 | 1 | |||
| Hypertension | ||||
| No | 2.361 | 1.331 | 4.186 | 0.003 |
| Yes | 1 | |||
| Hand–foot syndrome | ||||
| No | 2.995 | 1.835 | 4.888 | <0.0001 |
| Yes | 1 | |||