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Evaluating additional mechanisms of action for m909 antibody. (a) Cells grown in the presence or absence of 10 μg/mL of m909 over time in days. (b) Complement-dependent specific cytotoxicity for cell lines in presence of 10 μg/mL of m909, Herceptin, or human IgG1 with human serum. Samples tested in triplicate. (c) Percentage of cells with early and late markers of apoptosis after 24 h of incubation with and without 10 μg/mL m909. All error bars represent standard deviation.
