Table 3.

Predicted miRNAs targeted by hub gene. Bold miRNAs are top signification miRNA of upregulated and downregulated hub gene.

S. No.	Hub gene	Predicted top 10 miRNA
1.	IL6	hsa-miR-202-3p, hsa-let-7c-3p, hsa-let-7b-5p, hsa-miR-34a-5p, hsa-let-7a-5p and hsa-miR-98-5p
2.	TNF	hsa-miR-17-5p, hsa-miR-34a-5p and hsa-miR-203a-3p
3.	VEGFA	hsa-miR-17-5p hsa-miR-330-3p hsa-miR-200b-3p hsa-miR-20b-5p hsa-miR-20a-5p hsa-miR-106a-5p hsa-miR-141-5p hsa-miR-374b-5p hsa-miR-125a-3p hsa-miR-126-5p hsa-miR-378a-3p hsa-miR-34a-5p hsa-miR-335-5p hsa-miR-203a-3p hsa-miR-369-3p
4.	CXCL8	hsa-miR-202-3p hsa-let-7b-5p hsa-let-7f-5p hsa-miR-335-5p hsa-let-7d-5p hsa-let-7a-5p hsa-let-7c-5p hsa-miR-203a-3p hsa-miR-98-5p hsa-let-7g-5p hsa-miR-106a-5p
5.	IL1B	hsa-miR-106a-5p
6.	STAT1	hsa-miR-34a-5p hsa-miR-203a-3p
7.	FN1	hsa-miR-200b-3p hsa-let-7g-5p
8.	MYC	sa-miR-34b-5p hsa-miR-17-5p hsa-miR-196a-5p hsa-let-7b-5p hsa-miR-148a-3p hsa-miR-129-2-3p hsa-miR-98-5p hsa-let-7g-5p hsa-miR-20a-5p hsa-miR-599 hsa-miR-449c-5p hsa-miR-125a-3p hsa-miR-126-5p hsa-miR-378a-3p hsa-let-7f-5p hsa-miR-34a-5p hsa-miR-335-5p hsa-let-7d-5p hsa-miR-320b hsa-let-7a-5p hsa-let-7c-5p hsa-miR-33b-5p
9.	ICAM1	hsa-miR-17-5p hsa-miR-335-5p hsa-miR-17-3p hsa-miR-98-5p hsa-miR-141-5p