Skip to main content
. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: J Physiol. 2021 Jan 31;599(6):1833–1854. doi: 10.1113/JP281014

Figure 1. CBA/CaJ mice show age-related hearing loss (ARHL).

Figure 1.

(A) Example ABR waveforms from mice at different ages to clicks at different intensities. Red dots mark the positive and negative peaks of ABR wave I at 80 dB SPL. Thick traces: ABR threshold trace. Scale: 2 ms, 5 μV.

(B) ABR click thresholds in 32 young, 22 middle-aged, and 43 old mice. Dunn’s multiple comparisons test: **p < 0.001; ****p < 0.0001. ABR threshold was beyond 85 dB SPL in 12 old mice and not determined.

(C) Growth curves of ABR wave I amplitude in all mice. Thin lines: individual mice; thick lines: average of each age group, with error bars represent SEM.