Table 4.

Runs of homozygosity analysis results

Population	NSEG	Mb	MbA	Fhat1	Fhat2	Fhat3
SAS	44.7 [1.8]	193.5 [11.1]	3.93 [0.10]	0.098 [0.005]	0.106 [0.005]	0.102 [0.005]
EUR	19.5 [1.4]	31.9 [2.7]	1.62 [0.05]	0.037 [0.016]	0.030 [0.010]	0.034 [0.011]
FIN all	24.6 [0.8]	46.8 [2.0]	1.88 [0.04]	0.025 [0.003]	0.035 [0.004]	0.030 [0.002]
FIN Kainuu	26.1 [1.0]	50.9 [2.4]	1.94 [0.04]	0.030 [0.004]	0.033 [0.005]	0.032 [0.002]
FIN Western	24.3 [1.4]	45.1 [4.0]	1.85 [0.11]	0.017 [0.005]	0.049 [0.006]	0.033 [0.005]

NSEG Number of runs of homozygosity (minimum 1 Mb)

Mb Total length of runs (Mb)

MbA Average length of runs (Mb)

Fhat1 inbreeding coefficient 1: Variance-standardized relationship minus 1

Fhat2 inbreeding coefficient 2: Excess homozygosity-based inbreeding estimate

Fhat3 inbreeding coefficient 3: Estimate based on correlation between uniting gametes

brackets indicated standard error of mean

EUR: Non-Finnish European ancestry (outbred); SAS: South Asian ancestry (inbred); FIN: Finnish ancestry