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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Proteomics Clin Appl. 2021 Apr 26;15(2-3):e2000072. doi: 10.1002/prca.202000072

Figure 3. Pairwise Pearson correlations.

Figure 3.

(A) Pairwise Pearson correlation across all samples. Samples are separated by sex and disease state. Within disease/sex groups, samples are ordered by age with youngest samples at left on the x-axis and at top on y-axis. Black boxes indicate comparisons expanded in B and C. (B) Scatterplot of z-score normalized protein expression between youngest male AD+ sample and youngest female AD+ sample. Points are colored by significance when including age as explanatory variable in linear model (C) Scatterplot of z-score normalized expression between youngest male AD+ sample and oldest male AD+ sample. A high number of age-related proteins are present in the quadrants driving protein correlations in both B and C.