Table 1.
Patient demographics and baseline characteristics.
No. of Patients |
IV | SQ | |
---|---|---|---|
Total number of patients treated | 21 | 9 | 12 |
Sex | |||
Male | 10 (48) | 5 (56) | 5 (42) |
Female | 11 (52) | 4 (44) | 7 (58) |
Age years | 63 (53-80) | 62 (57-79) | 64 (53-80) |
iNHL Diagnosis | |||
FL | 16 (76) | 6 (67) | 10 (83) |
MZL | 4 (19) | 2 (22) | 2 (17) |
SLL | 1 (5)) | 1 (11) | 0 (0) |
FLIPI risk (FL patients) | N=16 | N=6 | N=10 |
low | 1 (6) | 0 (0) | 1 (10) |
Int | 8 (50) | 2 (33) | 6 (60) |
High | 7 (44) | 4 (67) | 3 (30) |
Ann Arbor stage | |||
I | 1 (5) | 0 (0) | 1 (8) |
II | 3 (14) | 2 (22) | 1 (8) |
II | 7 (33) | 3 (33) | 4 (33) |
IV | 10 (48) | 4 (44) | 6 (50) |
Time since last treatment to N803 | 25 (1-134) | 20 (1-88) | 38 (1-134) |
Median (range),months | |||
Time since last anti-CD20 to N803 | 27 (1-134) | 22 (2-88) | 52 (2-134) |
Median (range), months | |||
Anti-CD20 status | |||
Sensitive | 16 (76) | 7 (78) | 9 (75) |
Refractory | 5 (24) | 2 (22) | 3 (25) |
Number of prior treatments | 2 (1-7) | 2 (1-7) | 2 (1-7) |
Median (range), n | |||
Prior Therapies | |||
Chemotherapy combination | 17 (81) | 8 (89) | 9 (75) |
Anti-CD20 monotherapy | 4 (19) | 1 (11) | 3 (25) |
Lenalidomide | 1 (5) | 1 (11) | 0 (0) |
PI3K inhibitor | 2 (10) | 1 (11) | 1 (8) |
BTK inhibitor | 2 (10) | 2 (22) | 0 (0) |
Radioimmunoconjugate | 1 (5) | 0 (0) | 1 (8) |
Auto SCT | 1 (5) | 1 (11) | 0 (0) |
Number of prior anti-CD20 treatments Median (range), n | 2 (1-4) |