Table 1.
Cox regression analyses of factors associated with OS and TTR of HCC patients (n = 96).
| Variables | Overall survival | Time to recurrence | ||
|---|---|---|---|---|
| Hazard ratio (95%CI) | P-value | Hazard ratio (95%CI) | P-value | |
| Sex (female vs. male) | 1.011 (0.987–1.034) | 0.371 | 1.014 (0.991–1.038) | 0.226 |
| Age, Y (≤51 vs. >51) | 1.671 (0.571–1.504) | 0.759 | 0.797 (0.492–1.294) | 0.359 |
| Tumor differentiation (III–IV vs. I–II) | 2.625 (0.629–4.440) | 0.303 | 1.626 (0.683–3.870) | 0.272 |
| AFP (ng/mL; >20 vs. ≤20) | 1.518 (0.762–3.023) | 0.235 | 1.019 (0.529–1.965) | 0.955 |
| HbsAg (negative vs. positive) | 1.055 (0.443–2.513) | 0.904 | 1.099 (0.438–2.757) | 0.841 |
| Liver cirrhosis (no vs. yes) | 0.990 (0.463–2.114) | 0.978 | 1.002 (0.439–2.288) | 0.996 |
| Tumor number (multiple vs. single) | 1.056 (0.405–2.775) | 0.911 | 0.817 (0.323–2.064) | 0.669 |
| Tumor encapsulation (yes vs.no) | 1.131 (0.478–2.667) | 0.779 | 1.491 (0.646–3.474) | 0.353 |
| Vascular invasion (yes vs.no) | 2.625 (1.483–2.625) | 0.001** | 2.027 (1.152–3.570) | 0.014* |
| TNM stage (III–IV vs. I–II) | 1.958 (1.079–3.553) | 0.027* | 1.815 (1.024–3.217) | 0.041* |
| H2A.Z (high vs. low) | 2.917 (1.456–5.845) | 0.003** | 2.377 (1.250–4.522) | 0.008** |
H2A.Z H2A histone family member Z, TNM tumor, node, and metastasis, AFP alpha-fetoprotein.
*p < 0.05, **p < 0.01.