Table 2.
Expression of H2A.Z by immunohistochemical and clinicopathologic features of HCC patients (n = 96).
| Variables | Expression of H2A.Z low (40) high (56) |
p | |
|---|---|---|---|
| Sex | |||
| Female | 19 | 28 | 0.81 |
| Male | 21 | 28 | |
| Age (years) | |||
| ≤51 | 19 | 25 | 0.78 |
| >51 | 21 | 31 | |
| Preoperative AFP(ng/mL) | |||
| ≤20 | 8 | 14 | 0.57 |
| >20 | 32 | 41 | |
| HBsAg | |||
| Negative | 16 | 19 | 0.54 |
| Positive | 24 | 37 | |
| Liver cirrhosis | |||
| No | 15 | 15 | 0.20 |
| Yes | 25 | 44 | |
| Tumor size (cm) | |||
| ≤5 | 22 | 21 | 0.09 |
| >5 | 18 | 35 | |
| Tumor number | |||
| Single | 28 | 42 | 0.59 |
| Multiple | 12 | 14 | |
| Tumor encapsulation | |||
| No | 16 | 30 | 0.19 |
| Yes | 24 | 26 | |
| Vascular invasion | |||
| No | 29 | 14 | <0.01** |
| Yes | 11 | 42 | |
| TNM stage | |||
| I | 19 | 10 | 0.003** |
| II | 14 | 26 | |
| III | 7 | 20 | |
| Tumor differentiation | |||
| I–II | 29 | 25 | 0.007** |
| III–IV | 11 | 31 | |
H2A.Z H2A histone family member Z, TNM tumor, node, and metastasis, AFP alpha-fetoprotein.
**p < 0.01.