Table 4.
Factors associated with deep VD defects from OCTA.
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| Exp(ß) | 95% CI | p Value | Exp(ß) | 95% CI | p Value | |
| Disc hemorrhage | 1.531 | 0.245 to 9.574 | 0.649 | |||
| Axial length | 1.020 | 0.774 to 1.344 | 0.887 | |||
| SITA 24-2 MD (dB) | 0.924 | 0.706 to 1.209 | 0.565 | |||
| SITA 24-2 sensitivity (dB) | 0.825 | 0.573 to 1.188 | 0.288 | 0.864 | 0.600 to 1.244 | 0.432 |
| RNFL OCT variables | ||||||
| cpRNFL thickness | 0.994 | 0.951 to 1.039 | 0.788 | |||
| Rim area | 2.540 | 0.481 to 13.429 | 0.272 | 2.094 | 0.124 to 34.798 | 0.606 |
| Disc area | 1.528 | 0.677 to 3.451 | 0.297 | 1.110 | 0.199 to 6.208 | 0.905 |
| Average C/D ratio | 0.733 | 0.025 to 21.331 | 0.857 | |||
| Vertical C/D ratio | 0.970 | 0.032 to 29.428 | 0.986 | |||
| Cup volume | 1.214 | 0.268 to 5.513 | 0.801 | |||
| LC thickness (μm) | 0.980 | 0.967 to 0.993 | 0.003 | 0.980 | 0.962 to 0.999 | 0.041 |
| LC depth (μm) | 0.999 | 0.997 to 1.001 | 0.524 | |||
| Prelaminar thickness (μm) | 0.998 | 0.990 to 1.006 | 0.651 | |||
| Macular VD (%) | ||||||
| Superficial layer | 1.043 | 0.866 to 1.257 | 0.656 | |||
| Deep layer | 1.000 | 0.868 to 1.153 | 0.997 | |||
Variables with p values < 0.3 on univariate analysis were included in the multivariate analysis. p value threshold of 0.3 was designated to include multiple variables in the multivariate analysis. VD: vessel density; OCTA: optical coherence tomography angiography; MD: mean deviation; LC: lamina cribrosa.