Figure 3.

GSIS in MIN6 cells stimulated with 1-GERA-LPC, 1-GA-LPC, 1-CA-LPC, 1-FARA-LPC, and corresponding acids (GERA, GA, CA, FARA) at 5, 10 and 25 μM concentrations (A–C, respectively) versus compound solvent control (DMSO:EtOH). Results are presented as means ± SEM from 6 independent experiments, 4 biological replicates each. Secreted insulin was quantified at 2 mM glucose (open bars) and 20 mM glucose conditions (closed bars). p < 0.05 for secretion was significantly different from 2 mM glucose control (^) or 20 mM glucose control (*).