Table 1.
Impact of different factors on ZNF-281 H-score (protein) level. Clinical characteristics of 66 patients with H-score.
| Sex | Age | Hypertension | Diabetes | Radiotherapy | Chemotherapy | Alcohol Abuse | Cigarette Smoking | Surgical Resection | Grade | AJCC Stage | Classification | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T | N | |||||||||||
| N (%) | Media (range) | 0 = no, 1 = yes (%) | (1–3): N (%) | (1–4): N (%) | (1–4): N (%) | (0–3): N (%) | ||||||
| Female 20 (30.3) |
60 (40–83) |
0: 34 (51.5) | 0: 57 (86.4) | 0: 33 (50) | 0: 62 (93.9) | 0: 53 (80.3) | 0: 19 (28.8) |
0: 14 (21.2) | 1: 29 (43.9) | 1: 16 (24.2) | 1: 16 (24.4) | 0: 38 (57.6) |
| 2: 30 (45.5) | 2: 13 (19.7) | 2: 22 (33.3) | 1: 9 (13.6) | |||||||||
| Male 46 (69.7) |
1: 32 (48.5) | 1: 9 (13.6) | 1: 33 (50) | 1: 4 (6.1) | 1: 13 (19.7) | 1: 47 (71.2) |
1: 52 (78.8) | 3: 11 (16.7) | 3: 13 (19.7) | 2: 13 (19.7) | ||
| 3: 7 (10.6) | 4: 26 (39.4) | 4: 15 (22.7) | 3: 6 (9) | |||||||||
| Protein | ||||||||||||
| p = 0.903 | p = 0.175 | p = 0.19 | p = 0.501 | p = 0.006 | p = 0.095 | p = 0.765 | p = 0.599 | p = 0.234 | p < 0.001 | p < 0.001 | p = 0.0934 | p = 0.3119 |
For the group of 82 patients (66 with OSCC + 16 controls, H-score), the p-value was estimated to find any significant difference in ZNF-281 level according to Grade, AJCC Stage and T and N classifications with the Kruskal–Wallis one-way ANOVA test, whereas that according to other parameters was estimated with the Mann–Whitney U test.