Table 3.

Drug targets and multiple-molecule drugs for preventing skin aging from middle age to old age.

Target	MMP9	IL6	BCL2	CASP3
Drug
allantoin	●	●
diclofenac	●
mepyramine	●		●
resveratrol			●	●
azathioprine			●	●

●: Proposed small molecules target to the identified biomarkers (drug targets).