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DON reduces mitochondrial respiration in growth factor-stimulated VSMCs. (A) and (C) OCR kinetic traces in FBS (A)- and PDGF (C)-stimulated VSMCs treated with or without DON. (B) and (D) Rates of basal, maximal, and ATP-linked respiration in FBS (B)- and PDGF(D)-stimulated VSMCs treated with or without DON. Data are expressed as the mean ± SEM (n = 3 technical replicates). * p < 0.05 and ** p < 0.01.
