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. 2021 Jun 1;13(11):2740. doi: 10.3390/cancers13112740

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Bone marrow transplantation does not affect cardiac function and blood flow. (A) Schematic representation of bone marrow transplantation (BMT) procedure and subsequent mouse treatment. (B) Schematic representation of BMT experiment design. (C–H) Echo data show the difference between Ctr and BMT group mice in LVEF, LVFS, MV E/A Ratio, MV ET, LVAW;d, and LVPW;d. N = 5 mice/group. n.s. indicates not statistically significant by the GraphPad t test. LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening; MV E/A Ratio, mitral valve peak E and A velocity ratio; MV ET, mitral valve ejection time; LVAW;d, left ventricular anterior wall thickness in diastole; LVPW;d, left ventricular posterior wall thickness in diastole; Ctr, control; BMT, bone marrow transplantation.

Bone marrow transplantation does not affect cardiac function and blood flow. (A) Schematic representation of bone marrow transplantation (BMT) procedure and subsequent mouse treatment. (B) Schematic representation of BMT experiment design. (C–H) Echo data show the difference between Ctr and BMT group mice in LVEF, LVFS, MV E/A Ratio, MV ET, LVAW;d, and LVPW;d. N = 5 mice/group. n.s. indicates not statistically significant by the GraphPad t test. LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening; MV E/A Ratio, mitral valve peak E and A velocity ratio; MV ET, mitral valve ejection time; LVAW;d, left ventricular anterior wall thickness in diastole; LVPW;d, left ventricular posterior wall thickness in diastole; Ctr, control; BMT, bone marrow transplantation.