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Peptide conjugation to alginate with help of DMTMM coupling. (a) Scheme of the reaction; (b) 1H NMR spectrum of sodium alginate measured in D2O at 50°C (bottom); 1H NMR spectrum of Alg-TYRAY(DMTMM) measured in D2O at 50 °C (middle); 1H NMR spectrum of Alg-TYRAY(DMTMM*) measured in D2O at 50 °C (top). Specific signals proving the modification are marked with color.
