Table 2.
Overview of programmed clinical parameters in the randomized clinical trials.
| Study | Parameters | Telemedicine-Based Disease Management |
|---|---|---|
| TRUST [21] | VT, VF, SVT, ineffective 30-J shock, mode switch duration >10% in 24 h | No |
| CONNECT [22] | AT/AF burden, ventricular rate during AT/AF, number of shocks delivered, all therapies exhausted in a zone | No |
| EVOLVO [23] | Thoracic impedance (OptiVol), AT/AF burden, number of shocks delivered | Yes |
| ECOST [24] | VT, VF, SVT, ineffective 30-J shock, >75% (18 h) spent in mode switch | No |
| IN-TIME [25] | VT, VF, SVT, % biventricular pacing, PVC/h, patient activity | Yes |
| CONNECT OptiVol [26] | Thoracic impedance (OptiVol) | Yes |
| OptiLink HF [27] | Thoracic impedance (OptiVol) | Yes |
| REM-HF [28] | Thoracic impedance, % biventricular pacing, AT/AF burden, ventricular arrhythmias, activity level, heart rate variability | Yes |
| MORE-CARE [29] | Thoracic impedance (OptiVol), AT/AF burden | Yes |
AF = atrial fibrillation; AT = atrial tachycardia; PVC = premature ventricular complex; SVT = supraventricular tachycardia; VF = ventricular fibrillation; VT = ventricular tachycardia.