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Anti-FOXO3 staining (n = 5) of (a) wildtype (SGPL1+/+) and (b) SGPL1 knockout (SGPL−/−) colon sections and (c) SGPL1 knockout colon tumor sections after CAC induction (9 weeks); (magnification 40× in ‘overview’). CAC = colitis associated colon cancer; in image: t = Crypt tip; b = crypt bottom.
