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Concentration-dependent effects of the acute (black circles) and subchronic (blue circles) administrations of (A) clozapine (CLZ: 1, 3, 10 and 30 μM), (B) quetiapine (QTP: 0.3, 1, 3 and 10 μM) and (C) brexpiprazole (BPZ: 0.1, 0.3, 1 and 3 μM) on the basal astroglial l-glutamate release. Ordinate: mean ± SD (n = 6) of the basal astroglial l-glutamate release (μM), and abscissa: concentration of CLZ, QTP and BPZ (μM).
