Figure 4.
Effects of selective Cx43 inhibitor, N-terminal transactivator of transcription GAP19 (TAT-GAP19) on stimulatory effects of antipsychotics, CLZ (30 μM), QTP (10 μM) and BPZ (3 μM), on basal (A) and FCHK-evoked (B) astroglial l-glutamate releases. Ordinate: mean ± SD (n = 6) of astroglial l-glutamate release (μM). Light and dark color columns indicate the incubation without (non) and with TAT-GAP19, respectively. * p < 0.05, ** p < 0.01: relative to non, @@ p < 0.01 relative to control by MANOVA with Tukey’s post-hoc test.