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Second-order rate constants (k2) for the reaction of PL and its active analogs with cysteamine at 25 °C.
| Comps. | k2 (M−1 s−1) | Comps. | k2 (M−1 s−1) |
|---|---|---|---|
| PL-1 | 5.70 ± 0.24 | PL-6 | 8.96 ± 0.04 |
| PL | 2.26 ± 0.04 |
Reactions were carried out in Tris-HCl (100 mM, pH 7.4) and EDTA (2 mM, Ethylene Diamine Tetraacetic Acid)-ethanol (v/v, 2/1) under pseudo-first-order conditions. Data are expressed as the mean ± SD for three determinations.
