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. 2021 May 27;22(11):5746. doi: 10.3390/ijms22115746

Table 2.

Thrombotic effects of soybean-derived CGJ.

Model Strain Used in Fermentation Action Mode Reference
Raw soybean B. amyloliquefaciens MJ1-4 Repressing the growth of Aspergillus spp. producing aflatoxin B1 and Penicillium spp. producing ochratoxin by producing iturin or actively modified amino acids with 12,000–14,000 Da as a bacteriocin-like substance and another non-proteinaceous compound [70]
Raw soybean B. amyloliquefancies CH51 Producing fibrinolytic enzyme AprE51 similar to AprE homolog from B. subtilis [71]
Raw soybean B. subtilis 168 Improving fibrinolytic activity by genomic integration (amyE site) of aprE2, aprE176, and aprE179 gene [72]
Raw soybean B. subtilis CH3-5 Producing fibrinolytic enzyme AprE2 (29 kDa) [74]
Raw soybean B. subtilis HK176 Producing thermostable fibrinolytic enzyme AprE176 [73]
Raw soybean B. amyloliquefaciens CH86-1 Producing fibrinolytic enzyme Bpr86-1 [75]
Raw soybean B. amyloliquefaciens CB1 Producing fibrinolytic enzyme AprECB1 (28 kDa) as a serine metalloprotease in B. subtilis WB600; exhibiting the highest specificity for N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide, known as a substrate [76]
Male Sprague–Dawley rats B. licheniformis ATCC1071 Activating a plasmin-like protease that degrades fibrin clots, but not plasminogen; inhibiting collagen-induced platelet aggregation [67]