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. 2021 May 30;22(11):5884. doi: 10.3390/ijms22115884

Figure 7.

Figure 7

The effect of palmitic acid (PA) and magnesium isoglycyrrhizinate (MGIG) on the gene expression of (A) the triglyceride synthesis enzymes GPAT1/2/3/4 and DGAT1 and (B) the reticulum stress-related factors ATF6, BIP, and CHOP. Data are expressed as the mean ± SD (n = 5). The Control group was untreated cells; the PA group was cells administered 0.2 mM PA for 24 h; and the PA + MGIG group was cells administered 0.2 mM PA plus 0.25 mM MGIG for 24 h. In the statistical analysis between the other groups and the control group, “ns” means p > 0.05, * p < 0.05, ** p < 0.01, and *** p < 0.001. In the statistical analysis between the PA group and PA + MGIG group, # p < 0.05 and ## p < 0.01. GPAT: Glycerol 3-phosphate acyltransferase; DGAT: Diacylglycerol acyltransferase; ATF6: Activating transcription factor 6; BIP: Binding immunoglobulin protein; CHOP: C/EBP-homologous protein.