Table 2.

circRNAs with a regulatory effect in cancer progression through the MAPK signaling pathway.

Cancer	CircRNA	Gene of Origin	Interactions	Effect	Reference
Breast cancer	circ_0006528	PRELID2	miR-7-5p	Promotes cancer progression	[86]
	circ-WWC3	WWC3	miR-26b-3p, miR-660-3p		[87]
Ovarian	circ-ITCH	ITCH	miR-145-5p/RASA1	Suppresses cancer progression	[88]
	circ-PIP5K1A	PIP5K1A	miR-661/IGFBP5	Promotes cancer progression	[78]
	circ_102958	-	miR-1205/SH2D3A		[89]
Cervical cancer	circ-SMARCA5	SMARCA5	miR-432-5p	Promotes cell proliferation	[90]
	circ-AGFG1	AGFG1	miR-370-3p/RAF1	Promotes cancer progression	[80]
Clear Cell Renal Cell Carcinoma	circ-APBB1IP	APBB1IP	-	Promotes cancer progression	[91]
Bladder cancer	circ-CEP128	CEP128	miR-145-5p/MYD88	Promotes cancer progression	[92]
	circ-VANGL1	VANGL1	miR-1184/IGFBP2		[79]
Colorectal cancer	circ_102209	-	miR-761/RIN1	Promotes cell growth and metastasis	[76]
	circITGA7	ITGA7	miR-370-3p/NF1/ RREB1/ITGA7	Suppresses tumor growth and metastasis	[75]
Gastric cancer	circ_0032821	CEP128	-	Promotes cell proliferation and metastasis	[93]
	circ-PDSS1	PDSS1	miR-186-5p/NEK2	Promotes cancer progression	[82]
	circ-DLST	DLST	miR-502-5p/ NRAS/MAP2K1/MAPK1,miR-502-5p/ NRAS/MAP2K1/MAPK3		[81]
Hepatocellular carcinoma	circ-ASAP1	ASAP1	miR-326/MAPK1, miR-532-5p/MAPK1	Promotes cancer progression	[94]
Non-small cell lung cancer	circ-FOXM1	FOXM1	miR-1304-5p/PPDPF, miR-1304-5p/MACC1	Promotes cancer progression and metastasis	[95]
	circ-ZKSCAN1	ZKSCAN1	miR-330-5p/FAM83A	Promotes cancer progression	[83]