Table 3.

Biodistribution of ²²³RaA-silane-PEG and ²²³RaA-silane-PEG-D2B in BALB/c Nude mice at 4, 24, 72 h and 7 days post injection. Values are expressed as %ID g⁻¹ and presented as mean ± standard deviation.

223 RaA-silane-PEG		4 h	24 h	72 h	7 Days
	Blood	3.13 ± 1.07	0.3 ± 0.19	2.62 ± 0.77	0.61 ± 0.30
	Lungs	61.50 ± 37.46	5.5 ± 5.27	14.75 ± 9.81	3.75 ± 2.11
	Liver	116.0 ± 28.45	28.0 ± 18.6	36.57 ± 11.48	31.46 ± 10.13
	Spleen	79.6 ± 22.26	15.2 ± 13.02	5.54 ± 4.28	49.69 ± 19.01
	Kidneys	5.8 ±2.16	1.3 ± 0.86	1.05 ± 0.41	0.69 ± 0.15
	small intestine	1.0 ± 0.20	0.2 ± 0.18	0.03 ± 0.01	0.10 ± 0.03
	large intestine	1.2 ± 0.26	0.7 ± 0.47	0.45 ± 0.12	0.13 ± 0.05
	Stomach	0.9 ± 0.45	0.2 ± 0.08	1.65 ± 1.97	0.10 ± 0.02
	Bone	4.2 ± 1.60	3.0 ± 1.87	10.62 ± 2.50	13.23 ± 4.85
	Muscle	0.5 ± 0.43	0.2 ± 0.11	0.12 ± 0.11	0.32 ± 0.12
	Tumor	0.71 ± 0.72	0.40 ± 0.18	0.05 ± 0.07	0.11 ± 0.06
		4 h	24 h	72 h	7 Days
223 RaA-silane-PEG-D2B	Blood	1.0 ± 0.30	0.9 ± 0.41	4.11 ± 1.15	0.63 ± 0.39
	Lungs	20.2 ± 15.75	13.8 ± 13.51	33.80 ± 24.20	4.29 ± 1.58
	Liver	46.6 ± 7.11	62.5 ± 17.78	57.35 ± 8.68	43.55 ± 7.99
	Spleen	48.5 ± 5.24	36.6 ± 8.78	28.06 ± 24.74	128.57 ± 14.58
	Kidneys	2.3 ± 0.86	2.1 ± 0.37	1.81 ± 0.49	1.28 ± 0.29
	small intestine	0.6 ± 0.24	0.5 ± 0.09	0.09 ± 0.04	0.19 ± 0.10
	large intestine	0.7 ± 0.24	1.0 ± 0.66	0.61 ± 0.18	0.45 ± 0.22
	Stomach	0.3 ± 0.17	0.2 ± 0.10	1.29 ± 0.48	0.43 ± 0.35
	Bone	2.3 ± 1.42	5.7 ± 1.55	14.68 ± 6.40	15.02 ± 9.01
	Muscle	0.2 ± 0.07	0.3 ±0.19	0.27 ± 0.07	0.43 ± 0.16
	Tumor	0.23 ± 0.31	0.13 ± 0.19	0.24 ± 0.11	0.08 ± 0.03