Table 3.

Impact of each cardiovascular risk factor on the occurrence of major cardiovascular events during follow-up in ANCA-associated vasculitis patients from the OSTEOVAS cohort. The multivariate analysis was adjusted for the use of glucocorticoids and cyclophosphamide.

Cardiovascular Risk Factor (CVRF)	Patients Who Had MACEs among Those with This CVRF, n (%)	Patients Who Had MACEs among Those without This CVRF, n (%)	p-Value	OR (95% CI)
Older age (>50 for men; >60 for women)	14 (30.4%)	2 (3.5%)	0.001	14.71 (2.98–72.68)
Personal medical history of CVD	5 (45.5%)	11 (12%)	0.007	6.54 (1.66–25.71)
Sedentary lifestyle	7 (35%)	9 (10.8%)	0.011	4.50 (1.42–14.29)
Hypertension	13 (24.1%)	3 (6.1%)	0.017	5.04 (1.33–19.12)
Dyslipidemia	6 (31.6%)	10 (11.9%)	0.03	3.86 (1.14–13.09)
Obesity	4 (23.5%)	12 (14%)	0.32	1.93 (0.53–7.00)
Diabetes mellitus	2 (28.6%)	14 (14.6%)	0.34	2.38 (0.40–14.06)
Ever smoker	8 (18.6%)	8 (13.3%)	0.44	1.53 (0.52–4.47)

MACEs, major cardiovascular events; OR, odds ratio; CI, confidence interval; CVD, cardiovascular diseases.