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. 2021 May 27;13(11):2625. doi: 10.3390/cancers13112625

Table 1.

Summary of human tumor viruses.

Variable HPV HBV HCV EBV KSHV MCV HTLV-1
Full Name/
synonym
Human
Papilloma
Virus
Hepatitis B
Virus
Hepatitis C
Virus
Epstein–Barr Virus/
HHV-4
Kaposi
Sarcoma
Herpes
Virus/HHV-8
Merkel Cell
Polyoma
Virus
Human
T-cell Lymphotrophic
Virus, type-1
Family Papillomaviridae Hepadnaviridae Flaviviridae Herpesviridae Herpesviridae Polyomaviridae Retroviridae
Baltimore
System 1
Class I Class VII Class IV Class I Class I Class I Class VI
Virus
Genome
dsDNA ss/dsDNA +ssRNA lineardsDNA circulardsDNA dsDNA +RNA
Genome
Size
8 kbp 3 kb/kbp 9.5–12.5 kb 170 kbp 170 kbp 5.4 kbp 9 kbp
Virion
Size
52–60 nm 52–55 nm 40–60 nm 200 nm 100–150 nm 40–55 nm 100 nm
Envelope Absent Present Present Present Present Absent Present
Capsid Icosahedral Icosahedral Icosahedral Icosahedral Icosahedral Icosahedral Icosahedral
Vaccination Accessible Accessible Inaccessible Inaccessible Inaccessible Inaccessible Inaccessible
Anti-viral treatment Not established Effective Effective Occasionally
Effective
Not established Not established Not established
Diagnostic molecule p16 HBs antigen anti-HCV
antibody
EBER LANA CM2B4 ATLA

1 The details of Baltimore system are found in refs. [13,14]. Abbreviations: ATLA, anti-adult T-cell leukemia/lymphoma antibody; ds, double strands; EBER, EBV-encoded small RNA; LANA, Latency-associated nuclear antigen; ss, single strand; +, positive sense.