Table 5.
Association between hematolymphoid lesions and KSHV.
| Cell Linage | Diagnostic Entity (Abbreviation) |
Clonality | Common Features | References | Virus Negative Mimicry |
References |
|---|---|---|---|---|---|---|
| B | Primary effusion lymphoma (PEL) and its solid variants | Monoclonal | CD20-, HIV+/−, EBV+/− | [170,171] [257,258] | HHV8 negative common effusion lymphoma (HENCEL) |
[259] |
| B | HHV8-positive multicentric Castleman disease (HHV8+MCD) |
Polyclonal | MUM1+, CD138−, HIV+/−, EBV− | [252] | HHV8-negative multicentric Castleman disease (HHV8-MCD) |
[260] |
| B | HHV8-positive diffuse large B-cell lymphoma, NOS (HHV8+DLBCL) | Monoclonal | CD20+/−, CD79a-, CD138−, HIV+/−, EBV− | [253] | Plasmablastic lymphoma | [177,178] |
| B | HHV8-positive germinotropic lymphoproliferative disorder (GLPD) | Polyclonal/ oligoclonal |
MUM1+, CD138−, HIV−, EBV+ | [254,255,256] | Plasmablastic lymphoma | [177,178] |