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. 2021 May 28;22(11):5763. doi: 10.3390/ijms22115763

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Partial dependence on CRC for representative pairs of microbial/metabolomic features, shown as contour plots, coloured by log-odds of CRC. Higher values (yellow) indicate increased risk of CRC; lower values (blue) indicate decreased risk of CRC; a value of 0 indicates the risks are equal. Plots for more feature pairs can be found in Supplementary Figure S2. Top to bottom: (5-aminovalerate, harmane), (5-aminovalerate, 1,2-Dilinoleoyl-GPC), (5-aminovalerate, 1-oleoyl-2-linoleoyl-GPC), (guanosine, 5-aminovalerate).