Table 2.
Predictors of the treatment outcome in patients with diagnosed tuberculosis pleural effusion enrolled into treatment in RSSPMCPP, Tashkent, Uzbekistan, 2017–2018.
| Characteristics | Total | Successful Outcome | Unsuccessful Outcome | RR | 95% CI | p Value | |||
|---|---|---|---|---|---|---|---|---|---|
| n | % | n | (%) | n | (%) | ||||
| Age group | |||||||||
| <40 years | 86 | (57.7) | 79 | (91.9) | 7 | (8.1) | 1 | ||
| 40 years and over | 63 | (42.3) | 56 | (88.9) | 7 | (11.1) | 1.37 | (0.50–3.70) | 0.540 |
| Gender | |||||||||
| Male | 89 | (59.7) | 81 | (91.0) | 8 | (9.0) | 1 | ||
| Female | 60 | (40.3) | 54 | (90.0) | 6 | (10.0) | 1.11 | (0.41–3.04) | 0.836 |
| Region of referral | |||||||||
| Tashkent city | 30 | (20.1) | 29 | (96.7) | 1 | (3.3) | |||
| Tashkent region | 36 | (24.2) | 31 | (86.1) | 5 | (13.9) | |||
| Other cities ^ | 83 | (55.7) | 75 | (90.4) | 8 | (9.6) | |||
| Place of residence | |||||||||
| Urban | 41 | (27.5) | 37 | (90.2) | 4 | (9.8) | 1 | ||
| Rural | 108 | (72.5) | 98 | (90.7) | 10 | (9.3) | 0.95 | (0.32–2.86) | 0.926 |
| Drug-resistance | |||||||||
| Sensitive/not bac.confirmed | 143 | (96.0) | 131 | (91.6) | 12 | (8.4) | 1 | ||
| Confirmed RR/MDR | 6 | (4.0) | 4 | (66.7) | 2 | (33.3) | 3.97 | (1.13–13.93) | 0.031 |
| Smoking | |||||||||
| Yes | 37 | (24.8) | 35 | (94.6) | 2 | (5.4) | 1.98 | (0.46–8.45) | 0.355 |
| No | 112 | (75.2) | 100 | (89.2) | 12 | (10.7) | 1 | ||
| Alcohol use | |||||||||
| Yes | 9 | (6.0) | 9 | (100.0) | 0 | (0.0) | |||
| No | 140 | (94.0) | 126 | (90.0) | 14 | (10.0) | |||
| HIV | |||||||||
| Yes | 3 | (2.0) | 2 | (66.7) | 1 | (33.3) | 0.27 | (0.05–1.44) | 0.124 |
| No | 146 | (98.0) | 133 | (91.1) | 13 | (8.9) | |||
| Diabetes | |||||||||
| Yes | 3 | (2.0) | 2 | (66.7) | 1 | (33.3) | 3.74 | (0.70–20.13) | 0.124 |
| No | 146 | (98.0) | 133 | (91.1) | 13 | (8.9) | |||
| Hepatitis | |||||||||
| Yes | 5 | (3.4) | 3 | (60.0) | 2 | (40.0) | 4.80 | (1.44–15.98) | 0.011 |
| No | 144 | (96.6) | 132 | (91.7) | 12 | (8.3) | 1 | ||
| Other comorbidities * | |||||||||
| Yes | 19 | (12.8) | 16 | (84.2) | 3 | (15.8) | 1.87 | (0.57–6.09) | 0.301 |
| No | 130 | (87.2) | 119 | (91.5) | 11 | (8.5) | 1 | ||
RR: Risk ratio, CI: Confidence Interval, TPE: Tuberculosis pleurisy. * Other co-morbidities included arterial hypertension (9), coronary heart disease (5), lymphoma (1), pregnancy (1), epilepsy (1), chronic cholecystitis (1), chronic pyelonephritis (1). ^ Other cities of referral included: Andijon, Bukhara, Farghona, Jizzakh, Khorazm, Namangan, Nawoiy, Qashqadaryo, Samarqand, Sirdaryo, Surkhondaryo, and Karakalpakstan Republic.