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. 2021 May 28;13(11):2664. doi: 10.3390/cancers13112664

Table 4.

Summary of selected published studies on conventionally fractionated radiotherapy for skull base meningiomas.

Authors Patients (N) Technique Median Dose (Gy)/Fractions Median Volume (mL) Median Follow-Up (Months) Local Control Late Toxicity
Colombo et al., 2009 [108] 150 * CK 16–25/2–5 7.5 (0.1–64) 30 96 3.5
Fokas et al., 2014 [98] 49 * LINAC 25–35/5 6.11 (1.9–35.7) 50 92.9 at 5 and 87.5 at 10 years 12 (G2)
Han et al., 2014 [100] 22 * LINAC 25/5 4.8 (0.88–20.38) 32 95 0.7
Navarria et al., 2015 [109] 26 LINAC 25/5 13° 24.5 93% at 2 years G3, none
Marchetti et al., 2016 [110] 143 CK 21–25/2–5 8 (0.1–126.3) 44 93 at 5 years 5.1
Marchetti et al., 2019 [111] 168 CK 25/5 7.3 (0.1–76.8) 51 94% at 5 years 3.7

CK, CyberKnife; LINAC, linear accelerator; mean; * including skull base and intracranial meningiomas.