Table 4.
Authors | Patients (N) | Technique | Median Dose (Gy)/Fractions | Median Volume (mL) | Median Follow-Up (Months) | Local Control | Late Toxicity |
---|---|---|---|---|---|---|---|
Colombo et al., 2009 [108] | 150 * | CK | 16–25/2–5 | 7.5 (0.1–64) | 30 | 96 | 3.5 |
Fokas et al., 2014 [98] | 49 * | LINAC | 25–35/5 | 6.11 (1.9–35.7) | 50 | 92.9 at 5 and 87.5 at 10 years | 12 (G2) |
Han et al., 2014 [100] | 22 * | LINAC | 25/5 | 4.8 (0.88–20.38) | 32 | 95 | 0.7 |
Navarria et al., 2015 [109] | 26 | LINAC | 25/5 | 13° | 24.5 | 93% at 2 years | G3, none |
Marchetti et al., 2016 [110] | 143 | CK | 21–25/2–5 | 8 (0.1–126.3) | 44 | 93 at 5 years | 5.1 |
Marchetti et al., 2019 [111] | 168 | CK | 25/5 | 7.3 (0.1–76.8) | 51 | 94% at 5 years | 3.7 |
CK, CyberKnife; LINAC, linear accelerator; mean; * including skull base and intracranial meningiomas.