Table 2.
Statistical estimates for prediction of all-cause mortality by miR-126, Let-7, miR-223 and miR-125a-3p.
| miRNA | c-Index-AUC (95% CI) |
p | Cut-Off | Sensitivity, % | Specificity, % | Positive Predictive Value, % | Negative Predictive Value, % | Positive Likelihood Ratio |
|---|---|---|---|---|---|---|---|---|
| miR-126 | 0.75 (0.66–0.84) | <0.001 | 2.078 | 77% | 63% | 19% | 96% | 2.07 |
| Let-7e | 0.76 (0.63–0.82) | <0.001 | 0.8201 | 81% | 66% | 18% | 96% | 1.84 |
| miR-223 | 0.60 (0.50–0.70) | 0.094 | 6.617 | 77% | 49% | 15% | 95% | 1.49 |
| miR-125a-3p | 0.71 (0.60–0.82) | 0.001 | 0.0017 | 65% | 61% | 17% | 94% | 1.78 |
Abbreviations: AUC—area under the curve; 95% CI—95% confidence interval.