Figure 1.

Examples of HR point estimates (red circles) of effect size and their corresponding 0.95 CIs (blue horizontal lines). The areas shaded in gray represent clinically meaningful effect sizes. The top estimate is precise (narrow CI width) and compatible at the 0.05 level with clinically meaningful differences favoring the treatment group. The middle estimate is imprecise (wide CI width) and inconclusive because it is compatible at the 0.05 level with both clinically meaningful and non-meaningful effect sizes. The bottom estimate is precise (narrow CI width) and compatible at the 0.05 level with clinically non-meaningful differences.