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. 2021 May 27;18(11):5741. doi: 10.3390/ijerph18115741

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(a) Luciferase activity showed a significant reduction in vector containing DLC1 3′UTR (p < 0.0001) and WT-A (p < 0.05) but not in WT-B. (b) MT-B showed a significant reduction (p < 0.001) in luciferase activity, whereas there was no significant reduction in MT-A, and in MT-AB with the presence of miR-200c-3p. (c) With the presence of miR-200c-3p, luciferase activity showed a significant reduction in both wild-type vectors, WT-A (46bp) and WT-B (53bp), but not in mutant-types. Significant values are indicated as follows: * p < 0.05 and *** p < 0.001.

(a) Luciferase activity showed a significant reduction in vector containing DLC1 3′UTR (p < 0.0001) and WT-A (p < 0.05) but not in WT-B. (b) MT-B showed a significant reduction (p < 0.001) in luciferase activity, whereas there was no significant reduction in MT-A, and in MT-AB with the presence of miR-200c-3p. (c) With the presence of miR-200c-3p, luciferase activity showed a significant reduction in both wild-type vectors, WT-A (46bp) and WT-B (53bp), but not in mutant-types. Significant values are indicated as follows: * p < 0.05 and *** p < 0.001.