Table 1.
The receptor protein tyrosine phosphatases involved in insulin signaling or secretion.
Family | Representative Phosphatases | Gene | Described Implication in Insulin Action/Secretion |
---|---|---|---|
R1/R6 | CD45 | Ptprc | Yes |
R2A | LAR | Ptprf | Yes |
R2B | RPTP-κ | Ptprk | No |
R3 | DEP-1 | Ptprj | Yes |
R4 | RPTP-α, RPTP-ε | Ptpra, Ptpre | Yes |
R5 | RPTP-ζ, RPTP-γ | Ptprz, Ptprg | Yes |
R7 | PTPRR | Ptprr | Yes |
R8 | IA2 | Ptprn | Yes |