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. 2021 May 27;10(11):2368. doi: 10.3390/jcm10112368

Table 1.

Major risk factors associated with the development of intrahepatic cholangiocarcinoma.

Risk Factors for iCCA
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    Primary sclerosing cholangitis

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    Hepatolithiasis

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    Cirrhosis

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    Hepatitis B & C

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    Caroli’s disease

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    Liver flukes—Clonorchis sinensis, Opisthorchis viverrini

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    Obesity

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    Metabolic syndrome/non-alcoholic steatohepatitis

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    Alcohol consumption

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    Thorotrast