Skip to main content
. 2021 May 26;13(11):2607. doi: 10.3390/cancers13112607
3D-CRT 3-Dimensional conformal radiotherapy
ABVD Adriamycin [doxorubicin], bleomycin, vinblastine, and dacarbazine
ACT Adaptive T-cell therapy
ACVR1 Activin A receptor type I
AIEOP Assoziazione Italiana Ematologica Oncologia Pediatrica
AKT Protein kinase B
ALK Anaplastic lymphoma kinase
ALL Acute lymphoblastic leukemia
AML Acute myeloid leukemia
AML1 Acute myeloid leukemia 1
ASPL Alveolar soft part sarcoma locus
AT Ataxia-telangiectasia
ATRX Chromatin remodeler ATP-dependent helicase
BCL2 B-cell lymphoma 2
BCOR BCL-6 corepressor
BET Bromodomain and extra-terminal motif
BFM Berlin-Frankfurt-Muenster
BLM Bloom syndrome
BRAF v-raf murine sarcoma viral oncogene homolog B
BRCA2 Breast cancer 2
BTK Bruton tyrosine kinase
CAR Chimeric antigen receptor
CASP8 Caspase 8
CBFB Core-binding factor subunit beta
CD Cluster of differentiation
CDC5L Cell division cycle 5-like
CDK Cyclin-dependent kinase
CDKN2 Cyclin-dependent kinase inhibitor
CHK1 Checkpoint kinase 1
CHK2 Checkpoint kinase 2
CLL Chronic lymphocytic leukemia
CNS Central nervous system
CT Chemotherapy
CML Chronic myelogenous leukemia
CTLA-4 Cytotoxic T lymphocyte antigen-4
CTNNB1 Catenin beta-1
CXCL12 C-X-C motif chemokine 12
CXCR4 C-X-C chemokine receptor type 4
CYP Cytochrome P450
DNA Deoxyribonucleic acid
DNA-PK DNA-dependent protein kinase
DIPG Diffuse intrinsic pontine glioma
DS Down syndrome
EBV Epstein-Barr-Virus
EBRT External beam radiation therapy
EGFR Epidermal growth factor receptor
ERCC Excision repair cross-complementing
ERG ETS-related gene
ERK Extracellular signal-regulated kinase
EPN Ependymoma
ES Ewing sarcoma
EZH2 Enhancer of zeste homolog 2
FA Fanconi anemia
FBXW7 F-box/WD repeat-containing protein 7
FGFR Fibroblast growth factor receptor
FLI-1 Leukemia integration 1 transcription factor
FLT3 fms like tyrosine kinase 3
FOXO1 Forkhead box protein O1
GCCR German Childhood Cancer Registry
GST Glutathione s-transferase
HDAC Histone deacetylase
HER2 Human epidermal growth factor receptor 2
HGG High-grade glioma
HIC1 Hypermethylated in cancer 1
HL Hodgkin lymphoma
HSCT Hematopoietic stem cell transplantation
ICI Immune checkpoint inhibitor
IDH Isocitrate dehydrogenase isozymes
IFN Interferon
IGF1R Insulin-like growth factor 1 receptor
IGRT Image-guided radiotherapy
IKZF1 Ikaros family zinc finger protein 1
IL-2 Interleukin 2
IMRT Intensity-modulated radiotherapy
IR Ionizing radiation
ITD Internal tandem duplication
IVA Ifosfamide, vincristine, and actinomycin D
JAK2 Janus kinase 2
KRAS Kirsten rat sarcoma viral oncogene
KIT Tyrosine-protein kinase KIT
LFS Li–Fraumeni syndrome
LGG Low-grade gliomas
LIG4 DNA ligase 4
LSD1 Lysine-specific demethylase 1
MAPK Mitogen-activated protein kinase
MB Medulloblastoma
MDS Myelodysplastic syndrome
MET Mesenchymal-epithelial transition factor
MGMT O6-methylguanine DNA methyltransferase
MLL Mixed-lineage leukemia
MOPP Mustargen [mechlorethamine], oncovin [vincristine], procarbazine, and prednisone
MSH MutS homolog
MYC bHLH transcription factor
mTOR Mechanistic target of rapamycin
NB Neuroblastoma
NBS Nijmegen breakage syndrome
NF Neurofibroma
NF1 Neurofibromatosis 1
NF2 Neurofibromatosis 2
NF-kB Nuclear factor ‘kappa-light-chain-enhancer’ of activated B-cells
NHL Non-Hodgkin lymphoma
NKX2.2 Homeobox protein Nkx-2.2
NQO1 Nicotinamide adenine dinucleotide phosphate: quinone oxidoreductase
NRMS Nonrhabdomyosarcoma
NTRK Neurotrophic receptor tyrosine kinase
OP/EPA Vincristine, prednisone, procarbazine/etoposide, and doxorubicin
OPPA/COPP Cyclophosphamide, vincristine, prednisone, and procarbazine
OS Osteosarcoma
OTX2 Orthodenticle homeobox 2
PALB2 Partner and localizer of BRCA2
PAPPA Pregnancy-associated plasma protein A
PARP Poly(ADP-ribose)-polymerase
PAX3 Paired box gene 3
PD-1 Programmed cell death protein 1
PDGFR Platelet-derived growth factor receptor
PD-L1 Programmed cell death protein ligand 1
PI3K Phosphatidylinositol 3-kinase
PIK3CA Phosphatidylinositol-4,5-bisphosphate 3
PIM1 Proto-oncogene serine/threonine-protein kinase Pim-1
PMP22 Peripheral myelin protein 22
PRIM1 DNA primase small subunit
PTCH1 Patched homolog 1
PTEN Phosphatase and tensin homolog
PVT1 Plasmacytoma variant translocation 1
RAG1 Recombination activating gene 1
RARA Retinoic acid receptor alpha
RAS Rat Sarcoma viral oncogene
RASSF1A Ras association domain-containing
RB Retinoblastoma
RMS Rhabdomyosarcoma
RNA Ribonucleic acid
RR Relative risk
R/R Relapsed/refractory
RUNX1 Runt-related transcription factor 1
SBRT Stereotactic body radiotherapy
SEER Surveillance, epidemiology and end results
SHH Sonic hedgehog
SIR Standardized incidence ratio
SKP2 S-phase kinase-associated protein 2
SMARC SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily
SMR Standardized mortality ratio
SPM Second primary malignancy
STS Soft tissue sarcoma
SUFU Suppressor of fused homolog
TFE3 Transcription factor E3
TMZ Temozolomide
TNF Tumor necrosis factor
TRK Tyrosine receptor kinase
TP53 Tumor suppressor protein 53
TPMT Thiopurine methyltransferase
TPCV Thioguanine, procarbazine, lomustine, and vincristine
TSC Tuberous sclerosis complex
VAC Vincristine, actinomycin D, and cyclophosphamide
VACD Vincristine, cyclophosphamide, actinomycin D, and doxorubicin
VEGF Vascular endothelial growth factor
WRN Werner syndrome
XPD Xeroderma pigmentosum group D gene
XRCC1 X-ray cross-complementing factor 1
YAP1 Yes-associated protein 1