| 3D-CRT | 3-Dimensional conformal radiotherapy |
| ABVD | Adriamycin [doxorubicin], bleomycin, vinblastine, and dacarbazine |
| ACT | Adaptive T-cell therapy |
| ACVR1 | Activin A receptor type I |
| AIEOP | Assoziazione Italiana Ematologica Oncologia Pediatrica |
| AKT | Protein kinase B |
| ALK | Anaplastic lymphoma kinase |
| ALL | Acute lymphoblastic leukemia |
| AML | Acute myeloid leukemia |
| AML1 | Acute myeloid leukemia 1 |
| ASPL | Alveolar soft part sarcoma locus |
| AT | Ataxia-telangiectasia |
| ATRX | Chromatin remodeler ATP-dependent helicase |
| BCL2 | B-cell lymphoma 2 |
| BCOR | BCL-6 corepressor |
| BET | Bromodomain and extra-terminal motif |
| BFM | Berlin-Frankfurt-Muenster |
| BLM | Bloom syndrome |
| BRAF | v-raf murine sarcoma viral oncogene homolog B |
| BRCA2 | Breast cancer 2 |
| BTK | Bruton tyrosine kinase |
| CAR | Chimeric antigen receptor |
| CASP8 | Caspase 8 |
| CBFB | Core-binding factor subunit beta |
| CD | Cluster of differentiation |
| CDC5L | Cell division cycle 5-like |
| CDK | Cyclin-dependent kinase |
| CDKN2 | Cyclin-dependent kinase inhibitor |
| CHK1 | Checkpoint kinase 1 |
| CHK2 | Checkpoint kinase 2 |
| CLL | Chronic lymphocytic leukemia |
| CNS | Central nervous system |
| CT | Chemotherapy |
| CML | Chronic myelogenous leukemia |
| CTLA-4 | Cytotoxic T lymphocyte antigen-4 |
| CTNNB1 | Catenin beta-1 |
| CXCL12 | C-X-C motif chemokine 12 |
| CXCR4 | C-X-C chemokine receptor type 4 |
| CYP | Cytochrome P450 |
| DNA | Deoxyribonucleic acid |
| DNA-PK | DNA-dependent protein kinase |
| DIPG | Diffuse intrinsic pontine glioma |
| DS | Down syndrome |
| EBV | Epstein-Barr-Virus |
| EBRT | External beam radiation therapy |
| EGFR | Epidermal growth factor receptor |
| ERCC | Excision repair cross-complementing |
| ERG | ETS-related gene |
| ERK | Extracellular signal-regulated kinase |
| EPN | Ependymoma |
| ES | Ewing sarcoma |
| EZH2 | Enhancer of zeste homolog 2 |
| FA | Fanconi anemia |
| FBXW7 | F-box/WD repeat-containing protein 7 |
| FGFR | Fibroblast growth factor receptor |
| FLI-1 | Leukemia integration 1 transcription factor |
| FLT3 | fms like tyrosine kinase 3 |
| FOXO1 | Forkhead box protein O1 |
| GCCR | German Childhood Cancer Registry |
| GST | Glutathione s-transferase |
| HDAC | Histone deacetylase |
| HER2 | Human epidermal growth factor receptor 2 |
| HGG | High-grade glioma |
| HIC1 | Hypermethylated in cancer 1 |
| HL | Hodgkin lymphoma |
| HSCT | Hematopoietic stem cell transplantation |
| ICI | Immune checkpoint inhibitor |
| IDH | Isocitrate dehydrogenase isozymes |
| IFN | Interferon |
| IGF1R | Insulin-like growth factor 1 receptor |
| IGRT | Image-guided radiotherapy |
| IKZF1 | Ikaros family zinc finger protein 1 |
| IL-2 | Interleukin 2 |
| IMRT | Intensity-modulated radiotherapy |
| IR | Ionizing radiation |
| ITD | Internal tandem duplication |
| IVA | Ifosfamide, vincristine, and actinomycin D |
| JAK2 | Janus kinase 2 |
| KRAS | Kirsten rat sarcoma viral oncogene |
| KIT | Tyrosine-protein kinase KIT |
| LFS | Li–Fraumeni syndrome |
| LGG | Low-grade gliomas |
| LIG4 | DNA ligase 4 |
| LSD1 | Lysine-specific demethylase 1 |
| MAPK | Mitogen-activated protein kinase |
| MB | Medulloblastoma |
| MDS | Myelodysplastic syndrome |
| MET | Mesenchymal-epithelial transition factor |
| MGMT | O6-methylguanine DNA methyltransferase |
| MLL | Mixed-lineage leukemia |
| MOPP | Mustargen [mechlorethamine], oncovin [vincristine], procarbazine, and prednisone |
| MSH | MutS homolog |
| MYC | bHLH transcription factor |
| mTOR | Mechanistic target of rapamycin |
| NB | Neuroblastoma |
| NBS | Nijmegen breakage syndrome |
| NF | Neurofibroma |
| NF1 | Neurofibromatosis 1 |
| NF2 | Neurofibromatosis 2 |
| NF-kB | Nuclear factor ‘kappa-light-chain-enhancer’ of activated B-cells |
| NHL | Non-Hodgkin lymphoma |
| NKX2.2 | Homeobox protein Nkx-2.2 |
| NQO1 | Nicotinamide adenine dinucleotide phosphate: quinone oxidoreductase |
| NRMS | Nonrhabdomyosarcoma |
| NTRK | Neurotrophic receptor tyrosine kinase |
| OP/EPA | Vincristine, prednisone, procarbazine/etoposide, and doxorubicin |
| OPPA/COPP | Cyclophosphamide, vincristine, prednisone, and procarbazine |
| OS | Osteosarcoma |
| OTX2 | Orthodenticle homeobox 2 |
| PALB2 | Partner and localizer of BRCA2 |
| PAPPA | Pregnancy-associated plasma protein A |
| PARP | Poly(ADP-ribose)-polymerase |
| PAX3 | Paired box gene 3 |
| PD-1 | Programmed cell death protein 1 |
| PDGFR | Platelet-derived growth factor receptor |
| PD-L1 | Programmed cell death protein ligand 1 |
| PI3K | Phosphatidylinositol 3-kinase |
| PIK3CA | Phosphatidylinositol-4,5-bisphosphate 3 |
| PIM1 | Proto-oncogene serine/threonine-protein kinase Pim-1 |
| PMP22 | Peripheral myelin protein 22 |
| PRIM1 | DNA primase small subunit |
| PTCH1 | Patched homolog 1 |
| PTEN | Phosphatase and tensin homolog |
| PVT1 | Plasmacytoma variant translocation 1 |
| RAG1 | Recombination activating gene 1 |
| RARA | Retinoic acid receptor alpha |
| RAS | Rat Sarcoma viral oncogene |
| RASSF1A | Ras association domain-containing |
| RB | Retinoblastoma |
| RMS | Rhabdomyosarcoma |
| RNA | Ribonucleic acid |
| RR | Relative risk |
| R/R | Relapsed/refractory |
| RUNX1 | Runt-related transcription factor 1 |
| SBRT | Stereotactic body radiotherapy |
| SEER | Surveillance, epidemiology and end results |
| SHH | Sonic hedgehog |
| SIR | Standardized incidence ratio |
| SKP2 | S-phase kinase-associated protein 2 |
| SMARC | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily |
| SMR | Standardized mortality ratio |
| SPM | Second primary malignancy |
| STS | Soft tissue sarcoma |
| SUFU | Suppressor of fused homolog |
| TFE3 | Transcription factor E3 |
| TMZ | Temozolomide |
| TNF | Tumor necrosis factor |
| TRK | Tyrosine receptor kinase |
| TP53 | Tumor suppressor protein 53 |
| TPMT | Thiopurine methyltransferase |
| TPCV | Thioguanine, procarbazine, lomustine, and vincristine |
| TSC | Tuberous sclerosis complex |
| VAC | Vincristine, actinomycin D, and cyclophosphamide |
| VACD | Vincristine, cyclophosphamide, actinomycin D, and doxorubicin |
| VEGF | Vascular endothelial growth factor |
| WRN | Werner syndrome |
| XPD | Xeroderma pigmentosum group D gene |
| XRCC1 | X-ray cross-complementing factor 1 |
| YAP1 | Yes-associated protein 1 |