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. 2021 May 30;10(11):2426. doi: 10.3390/jcm10112426

Table 1.

Factors associated with perineural, lymphatic, and venous infiltration.

Pn1 Pn0 p L1 L0 p V+ V0 p
n = 41 n = 109 n = 21 n = 129 n = 27 n = 113
T-status 0.128 0.046 0.253
T1 + T2 27 85 12 100 25 87
T3 + T4 14 24 9 29 12 26
N-status * 0.019 0.010 0.121
N0 20 70 8 82 20 70
N1 18 25 11 32 15 28
M-status 0.723 0.085 0.861
M0 39 101 18 123 35 106
M1 2 7 3 6 2 7
Pn-status - <0.001 <0.001
Pn0 - - 9 100 17 92
Pn1 - - 12 29 20 21
L-status <0.001 - <0.001
L0 29 100 - - 22 92
L1 12 9 - - 13 6
V-status <0.001 <0.001 -
V0 21 92 6 92 - -
V1 + V2 20 17 13 22 - -
Grading 0.162 0.124 0.212
G1 + G2 22 72 10 84 20 74
G3 + G4 19 37 11 45 17 39
R-status 0.320 0.641 0.696
R0 34 97 19 112 33 98
R1 7 12 2 17 4 15
Multifocality 0.820 0.191 0.788
Yes 12 34 9 37 12 34
solitary 29 75 12 92 25 79
≥major resection 0.004 0.504 0.012
Yes 36 69 16 89 32 73
No 5 40 5 40 5 40
Extended resection 0.410 0.299 0.174
Yes 26 61 10 77 25 62
No 15 48 11 52 12 51
Visceral infiltration 0.015 0.406 0.250
Yes 10 10 4 16 7 13
No 31 99 17 113 30 100

Significant p-values in bold; * 17 patients with Nx were excluded from this analysis.