Table 1.
Some characteristics of compounds II–XIX.
| Samples | Elemental Analysis, Calc (Found) (%) | Chemical Formula | Yield (%) |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| C | H | N | S | O | Br | Cl | I | |||
| 1,4-disubstituted thiosemicarbazides (compounds II–VII) | ||||||||||
| II | 53.6 (53.9) |
3.9 (4.2) |
15.6 (16) |
17.9 (18.2) |
8.9 (7.7) |
- | - | - | C16H14N4O2S2 | 65 |
| III | 54.8 (55.1) |
4.3 (4.5) |
15.1 (15.4) |
17.2 (17.6) |
8.6 (7.4) |
- | - | - | C17H16N4O2S2 | 75 |
| IV | 52.6 (52.9) |
4.1 (4.3) |
14.4 (14.8) |
16.4 (16,9) |
12.5 (11.1) |
- | - | - | C17H16N4O3S2 | 85 |
| V | 43.9 (44.1) |
2.9 (3.2) |
12.8 (12.9) |
14.6 (15) |
7.4 (6.3) |
18.3 (18.6) |
- | - | C16H13N4O2S2Br | 80 |
| VI | 48.9 (49) |
3.3 (3.6) |
14.3 (14.6) |
16.3 (16.6) |
8.2 (6.8) |
- | 9 (9.5) |
- | C16H13N4O2S2Cl | 78 |
| VII | 39.7 (39.9) |
2.7 (2.9) |
11.6 (11.9) |
13.2 (13.6) |
6.6 (5.2) |
- | - | 26.2 (26.6) |
C16H13N4O2S2I | 77 |
| 1,3,4-thiadiazoles (compounds VIII–XIII) | ||||||||||
| VIII | 56.5 (56.6) |
3.5 (3.8) |
16.5 (16.8) |
18.8 (19.2) |
4.7 (3.6) |
- | - | - | C16H12N4OS2 | 89 |
| IX | 57.6 (58) |
4 (4.1) |
15.8 (16.1) |
18.1 (18.5) |
4.5 (3.3) |
- | - | - | C17H14N4OS2 | 83 |
| X | 52.1 (52.4) |
3.8 (4) |
15.1 (15.4) |
17.3 (17.6) |
11.7 (10.6) |
- | - | - | C17H14N4O2S2 | 81 |
| XI | 45.8 (46.2) |
2.6 (2.8) |
13.4 (13.6) |
15.3 (15.7) |
22.9 (21.7) |
19 (19.4) |
- | - | C16H11N4OS2Br | 79 |
| XII | 51.3 (51.4) |
2.9 (3.1) |
15 (15.3) |
17.1 (17.4) |
13.7 (12.8) |
- | 9.5 (9.7) |
- | C16H11N4OS2Cl | 74 |
| XIII | 41.2 (41.5) |
2.4 (2.6) |
12 (12.3) |
13.7 (14.1) |
30.7 (29.2) |
- | - | 27.3 (27.5) |
C16H11N4OS2I | 71 |
| 1,2,4-triazoles (compounds XIV–XIX) | ||||||||||
| XIV | 56.5 (56.7) |
3.5 (3.9) |
16.5 (16.9) |
18.8 (19.2) |
4.7 (3.3) |
- | - | - | C16H12N4OS2 | 66 |
| XV | 57.6 (57.8) |
4 (4.3) |
15.8 (16.2) |
18.1 (18.3) |
4.5 (3.4) |
- | - | - | C17H14N4OS2 | 74 |
| XVI | 55.1 (55.3) |
3.8 (4) |
15.1 (15.5) |
17.3 (17.7) |
8.7 (7.5) |
- | - | - | C17H14N4O2S2 | 88 |
| XVII | 45.8 (46) |
2.6 (3) |
13.4 (13.7) |
15.3 (15.7) |
22.9 (21.6) |
19 (19.3) |
- | - | C16H11N4OS2Br | 79 |
| XVIII | 51.3 (51.4) |
2.9 (3.3) |
15 (15.2) |
17.1 (17.4) |
13.7 (12.7) |
- | 9.5 (9.9) |
- | C16H11N4OS2Cl | 77 |
| XIX | 41.2 (41.4) |
2.4 (2.5) |
12 (12.4) |
13.7 (14) |
30.7 (29.7) |
- | - | 27.3 (27.6) |
C16H11N4OS2I | 74 |