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. 2021 May 28;22(11):5804. doi: 10.3390/ijms22115804

Figure 1.

Figure 1

Macroautophagy. The C-shaped expansion of the double membrane results in the formation of an autophagosome. This small ‘vesicle’ contains redundant or damaged organelles, cellular fragments or proteins. In the next step, the formed autophagosome fuses with the lysosome and an autolysosome is formed. Inside the created structure, all components are degraded by hydrolytic enzymes.