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. 2021 May 28;13(11):2654. doi: 10.3390/cancers13112654

Table 3.

The significant variants (with a p-value of minus four orders of magnitude or better) for different analysis on our data. The last column (additional association) gives information about more associations for the variant in our data or citations for that variant in other GWAS studies (PMIDs are provided). OR is odds ratio.

SNV BP Rs Id Gene p-Value OR Additional Association
Cancer (rPDAC + nrPC) vs. CP:
8:143561151 rs12541790 GSDMD 1.54×105 3.26 In particular, with nrPC
20:49633437 rs11471493 B4GALT5 5.11×105 2.60 rPDAC & CA19 False Negative (p-value = 2.81×104)
8:143562235 rs11551198 GSDMD 5.21×105 0.31
20:49634210 rs235032 B4GALT5 1.37×104 2.17 rPDAC & CA19 False Negative (p-value = 1.44×104)
16:3067936 rs2239303 IL32 1.91×104 0.43 Another GWAS study with acute lung, PMID: 21649914
4:128039414 rs11098945 ABHD18 3.72×104 0.47 Other GWAS studies with type 2 diabetes,
PMIDs: 26964836, 25774817, 25145545, 24843659 & 21490949
11:61127379 rs375347163 CD5 4.04×104 0.35
11:61127380 rs72912997 CD5 4.04×104 0.35
6:70579486 rs1048886 SDHAF4 6.16×104 0.43 Other GWAS studies with type 2 diabetes,
PMIDs: 26964836, 25774817, 25145545, 24843659 & 21490949
14:99169513 rs375191905 BCL11B 7.27×104 0.36
rPDAC vs. CP
12:9083754 rs1385820032 A2M 5.59×105 0.22
16:3067936 rs2239303 IL32 7.04×105 0.34
8:23188960 rs1334003684 RP11-1149O23.2 8.37×105 0.24
15:61856531 15:61856531 RP11-16B9.1 8.80×105 0.3
14:99169513 rs375191905 BCL11B 1.38×104 0.23
20:49633437 rs1555810424 B4GALT5 2.11×104 2.86 CA19 False Negative (p-value = 1.2×104)
20:49634210 rs235032 B4GALT5 2.24×104 2.49 CA19 False Negative (p-value = 1.2×104)
3:64000218 rs112759850 PSMD6-AS2 2.94×104 0.11
12:107733077 rs1045749 PRDM4 4.45×104 0.42
3:70957989 rs1387507994 FOXP1 4.48×104 0.27
13:52413342 rs13431 VPS36 6.70×104 2.36 Another GWAS study with Ulcerative colitis, PMID: 27902482
12:107733387 12:107733387 PRDM4 8.41×104 0.43
12:115821 rs66898998 MED13L 9.33×104 0.43
17:42315197 rs368910594 STAT3 9.54×104 0.33
17:50862895 17:50862895 TOB1 9.86×104 0.13
4:128039414 rs11098945 ABHD18 9.92×104 0.43
nrPC vs. CP
8:143561151 rs12541790 GSDMD 8.93×105 3.541
8:133458886 rs879077709 ST3GAL1 9.08×105 0.21
8:143562235 rs11551198 GSDMD 1.50×104 0.26
2:74969604 rs7881 POLE4 2.11×104 0.347
2:96834655 rs10643982 CNNM3 2.71×104 0.33
6:70579486 rs1048886 SDHAF4 3.72×104 0.3
8:17229247 rs1043093 CNOT7 7.59×104 0.12
17:1736164 rs11549259 WDR81 9.30×104 0.41
rPDAC vs. nrPC
12:131922463 rs3088051 ULK1 6.31×105 0.34 Another GWAS study with Crohn’s disease, PMID: 22536218
12:27755670 rs3751233 MRPS35 7.91×104 0.30
11:112084759 rs544184 C11orf57 8.01×104 2.17 Another GWAS study with colorectal cancer, PMID: 26377099