Table 1.
Baseline characteristics, medical history and characteristics during ICU stay.
| All Patients (n = 18) | Type H (n = 6) | Type L (n = 12) | p-Value | |
|---|---|---|---|---|
| Age, years | 61 ± 7 | 60 ± 10 | 61 ± 7 | 1.00 |
| Female, n (%) | 7 (39) | 4 (67) | 3 (25) | 0.14 |
| Comorbidities, n (%) | ||||
| COPD | 3 (17) | 1 (17) | 2 (17) | 1.00 |
| Bronchial asthma | 2 (11) | 1 (17) | 1 (8) | 1.00 |
| Hypertension | 11 (61) | 2 (33) | 9 (75) | 0.14 |
| Heart Failure | 1 (6) | 0 (0) | 1 (6) | 1.00 |
| Atrial fibrillation | 1 (6) | 0 (0) | 1 (8) | 1.00 |
| Chronic kidney disease | 2 (11) | 0 (0) | 2 (17) | 1.00 |
| Coronary artery disease | 3 (17) | 1 (17) | 2 (17) | 1.00 |
| Diabetes mellitus | 2 (11) | 1 (17) | 1 (8) | 1.00 |
| Symptom onset to, days | ||||
| Hospitalization | 7 ± 6 | 2 ± 3 | 9 ± 5 | 0.02 |
| Intensive care admission | 10 ± 5 | 6 ± 4 | 12 ± 4 | 0.04 |
| Intubation | 11 ± 4 | 7 ± 3 | 12 ± 4 | 0.03 |
| In-hospital Periods, days | ||||
| Fever days | 30 ± 12 | 31 ± 18 | 29 ± 10 | 0.91 |
| Hospital length of stay | 44 ± 16 | 50 ± 20 | 40 ± 14 | 0.33 |
| Oxygen supplementation | 39 ± 18 | 47 ± 23 | 35 ± 14 | 0.26 |
| Characteristics during ICU stay | ||||
| P/F Ratio at ICU admission | 143 ± 53 | 107 ± 47 | 162 ± 48 | 0.06 |
| Mean of P/F Ratio after 50% of the total duration of ventilation | 267 ± 81 | 293 ± 135 | 259 ± 61 | 0.90 |
| Total respiratory compliance in the first week, mL/cmH2O | 42 ± 22 | 25 ± 11 | 50 ± 21 | <0.01 |
| Total respiratory compliance in the third week, mL/cmH2O | 56 ± 37 | 28 ± 11 | 70 ± 38 | 0.07 |
| Duration of ICU stay, days | 34 ± 16 | 40 ± 22 | 31 ± 12 | 0.45 |
| Duration of Ventilation, days | 30 ± 15 | 34 ± 19 | 27 ± 12 | 0.61 |
| Patients on ECMO, n (%) | 2 (11) | 2 (33) | 0 (0) | 0.10 |
| Duration of ECMO, days | 13 ± 4 | 13 ± 4 | - | - |
| Prone position, n (%) | 13 (72) | 5 (83) | 8 (66) | 0.61 |
| Continuous neuromuscular blockade (NMB) > 6 h at any point, n (%) | 3 (17) | 0 (0) | 3 (25) | 0.51 |
| CRRT, n (%) | 7 (39) | 1 (17) | 6 (50) | 0.32 |
| Antibiotic therapy, n (%) | 17 (94) | 6 (100) | 11 (92) | 1.00 |
| Discharge to | ||||
| Rehabilitation, n (%) | 6 (33) | 2 (33) | 4 (33) | - |
| Other hospital, n (%) | 2 (11) | 1 (17) | 1 (8) | - |
| Home, n (%) | 10 (56) | 3 (50) | 7 (58) | - |
| Time from discharge to follow-up, days | 197 ± 15 | 198 ± 5 | 196 ± 18 | 0.96 |
Values are presented as mean ± standard deviation or number of patients (percentage). COPD = chronic obstructive pulmonary disease; CRRT = continuous renal replacement therapy; ECMO = Extracorporeal membrane oxygenation; ICU = intensive care unit; P/F = partial pressure of oxygen/fraction of inspired oxygen.