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. 2021 Jun 12;22:535. doi: 10.1186/s12891-021-04418-y

Table 2.

Univariate and multivariate Cox regression analysis of association between different factors and failure of core decompression

Coefficient Univariate analysis Multivariate analysis
Hazard Ratio P value 95% CI Hazard Ratio P value 95% CI
Ficat stage
 Stage I 1 (reference) <.001 1 (reference) 1 (reference) .641 1 (reference)
 Stage II A .781 .749 .171–3.565 1.741 .491 .359–8.432
 Stage II B 4.749 .035 1.115–20.221 1.162 .849 .249–5.413
Preoperative Harris score 1.051 .190 .976–1.132
Necrotic location
 A 1 (reference) <.001 1 (reference) 1 (reference) .582 1 (reference)
 B .418 .538 .026–6.698 .306 .411 .018–5.163
 C1 5.242 .111 .685–40.097 1.231 .857 .127–11.896
 C2 18.644 .004 2.494–139.395 1.458 .752 .140–15.145
Extent of necrotic lesion
  < 15% 1 (reference) <.001 1 (reference) 1 (reference) .001 1 (reference)
 15–30% 3.708 .109 .747–18.408 3.170 .196 .551–18.255
  > 30% 32.521 <.001 7.695–137.444 22.293 .001 2.506–141.752
Bone marrow edema 3.814 <.001 1.935–7.518 2.188 .046 1.015–4.719
Postoperative work intensity
 Grade 0–1 1 (reference) <.001 1 (reference) 1 (reference) .001 1 (reference)
 Grade 2 6.004 <.001 2.768–13.022 3.579 .002 1.583–8.092
 Grade 3–4 6.771 <.001 2.833–16.186 5.036 .001 1.863–13.615

Variables included in the multivariate model if univariate P value <.05