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. 2021 May 27;10(11):2343. doi: 10.3390/jcm10112343

Figure 1.

Figure 1

Histological features in SCC: (a) intense desmoplastic reaction (tumor/stroma ratio < 1) in non-keratinizing SCC; HE, original magnification 20×; (b) poor desmoplastic reaction (tumor/stroma ≥1) in moderately differentiated SCC; HE, original magnification 10×; (c) abundant immune infiltrate in keratinizing, well-differentiated SCC; HE, original magnification თ; (d) absence of tumor-infiltrating lymphocytes in moderately differentiated SCC, HE, and original magnification 4×; (e) high tumor-budding activity in moderately differentiated SCC; HE, original magnification 10×; (f) low tumor-budding activity in moderately differentiated SCC; HE, original magnification 10×; (g) extended necrotic areas in moderately differentiated SCC; HE, original magnification 20×; and (h) absence of necrotic areas in moderately differentiated SCC, keratinizing SCC; HE, original magnification 20×. SCC: Squamous cell carcinoma; HE: hematoxylin-eosin.