Table 2.

Correlation analysis between histological features and clinicopathological characteristics in SCC.

Variable	Tumor Stroma Ratio			Tumor Immune Response			Tumor Budding			Tumor Necrosis
	≤50%	>50%	p	Low	High	p	Low	High	p	High	Low	p
Gender			0.999			0.999			0.822			0.999
Male	15	58		24	49		37	36		12	61
Female	6	21		9	18		15	12		4	23
T stage			0.1358			0.0722			0.0077			0.0004
T1	5	23		8	20		22	6		1	27
T2	5	35		9	31		18	22		5	35
T3	5	11		7	9		7	9		1	12
T4A	6	10		9	7		5	11		9	10
Nodal status (n = 35) *			0.0275			0.002			0.3175			0.1774
pN0	2	15		3	14		10	7		1	16
pN+	9	9		13	5		7	11		5	13
TNM stage			0.0116			0.0043			0.0039			0.0143
I	3	24		7	20		22	5		1	26
II	3	30		5	28		15	18		5	28
III	5	9		6	8		5	9		1	13
IVA	10	16		15	11		10	16		9	17
Histological differentiation			0.2211			0.2306			0.328			0.7481
High	3	23		6	20		15	11		3	23
Intermediate	15	40		18	37		25	30		10	45
Low	3	16		9	10		12	7		3	16
Keratinization status			0.9319			0.6147			0.2909			0.708
Keratinizing	15	59		24	50		36	38		13	61
Non-keratinizing	3	11		6	8		10	4		2	12
Unknown	3	9		3	9		6	6		1	11
Perineural invasion			0.0006			0.0138			0.0454			0.999
Confirmed	7	3		7	3		2	8		1	9
Not confirmed	14	76		26	64		50	40		15	75
Locoregional reccurence			0.0026			0.0596			0.0292			0.5481
Present	12	17		14	15		10	19		6	23
Absent	9	62		19	52		42	29		10	61

* From a total of 35 neck dissections; statistical significance p < 0.05.