Table 1.
Collagen types, molecular formula, and tissue distribution. Reproduced from [46] with permission. Copyright (2010) MDPI AG.
Type | Molecular Formula | Polymerized Form | Tissue Distribution | |
---|---|---|---|---|
Fibril-Forming (fibrillar) | I | [α1(I)]2α2(I) | fibril | bone, skin, tendons, ligaments, cornea (represent 90% of total collagen of the human body) |
II | [α1(II)] | fibril | cartilage, intervertebral disc, notochord, vitreous humor in the eye | |
III | [α1(III)]3 | fibril | skin, blood vessels | |
V | [α1(V)]2α2(V) and α1(V)α2(V)α3(V) | fibril (assemble with type I) |
idem as type I | |
XI | α1(XI)α2(XI)α3(XI) | fibril (assemble with type II) |
idem as type II | |
Fibril-associated | IX | α1(IX)α2(IX)α3(IX) | lateral association with type II fibril | cartilage |
XII | [α1(XII)]3 | lateral association with type I fibril | tendons, ligaments | |
Network-forming | IV | [α1(IV)]2α2(IV) | sheet-like network | basal lamina |
VII | [α1(VII)]3 | anchoring | beneath stratified squamous epithelia |