Table 4.
Diagnostic performance of the 13C-UBT and 14C-UBT with optimal H. pylori-positive and -negative cutoff values, and the inclusion of an indeterminate range
| Method | Histology | Sens (%) 95%CI |
Spec (%) 95%CI |
Acc (%) 95%CI |
FPR (%) 95%CI |
FNR (%) 95%CI |
||
|---|---|---|---|---|---|---|---|---|
| + | – | |||||||
| 13C-UBT |
+ (≥ 10.4%) |
120 | 14 |
96 90.4–98.5 |
76.7 63.7–86.2 |
89.7 84.5–93.4 |
23.3 13.8–36.3 |
4 1.5–9.6 |
|
− (≤ 2.9%) |
5 | 46 | ||||||
|
IND (3–10.3%) |
18 | 14 | ||||||
| 14C-UBT |
+ (≥ 238 DPM) |
158 | 12 |
98.1 94.2–99.5 |
76.9 62.8–87.0 |
93 88.6–95.8 |
23.1 13.0–37.2 |
1.9 0.5–5.8 |
|
− (≤ 86 DPM) |
3 | 40 | ||||||
|
IND (87–237 DPM) |
31 | 23 | ||||||
UBT urea breath test, IND indeterminate, Sens sensitivity, Spec specificity, Acc accuracy, FPR false positive rate, FNR false negative rate, CI confidence interval