Table 2.
Predictors of septic AKI and RRT initiation
| AKI (n = 38) | RRT initiation (n = 6) | |
|---|---|---|
| Univariate analysis | Univariate analysis | |
| Variable | P -value | P -value |
| Age | 0.402 | 0.108 |
| Sex | 0.930 | 0.670 |
| Cancer | 0.236 | 0.383 |
| Coronary artery disease | 0.621 | none |
| Diabetes mellitus | 0.005 | 0.620 |
| Hypertension | 0.010 | 0.368 |
| Albumin | 0.851 | 0.137 |
| CRP | 0.023 | 0.773 |
| WBC | 0.253 | 0.606 |
| Neutrophil | 0.315 | 0.564 |
| Lymphocytes | 0.631 | 0.127 |
| Platelet count | 0.081 | 0.127 |
| Fibrinogen | 0.427 | 0.088 |
| Survival | 0.052 | 0.333 |
| ARDS | 0.069 | 0.035 |
| Shock | 0.080 | 0.641 |
| DIC | 0.000 | 0.206 |
| Presepsin on Day 1 | 0.001 | 0.149 |
| Presepsin on Day 2 | 0.009 | 0.019 |
| Presepsin on Day 3 | 0.143 | 0.905 |
| Presepsin on Day 5 | 0.185 | 0.053 |
| ΔPresepsin Day 2 - Day 1 | 0.810 | 0.032 |
| ΔPresepsin Day 3 - Day 1 | 0.530 | 0.811 |
| ΔPresepsin Day 5 - Day 1 | 0.408 | 0.053 |
| GPS | 0.232 | 0.832 |
| NLR | 0.969 | 0.837 |
| PLR | 0.032 | 0.458 |
| PI | 0.220 | 0.575 |
| PNI | 0.696 | 0.091 |
| iPS-GPS | 0.024 | 0.528 |
| iPS-NLR | 0.203 | 0.217 |
| iPS-PLR | 0.877 | 0.242 |
| iPS-PI | 0.025 | 0.782 |
| iPS-PNI | 0.172 | 0.718 |
| SOFA | 0.024 | 0.200 |
| qSOFA | 0.102 | 0.726 |
AKI acute kidney injury, RRT renal replacement therapy, CRP C-reactive protein, WBC white blood cell, ARDS acute respiratory distress syndrome, DIC disseminated intravascular coagulation, GPS Glasgow Prognostic Score, NLR neutrophil to lymphocyte ratio, PLR platelet to lymphocyte ratio, PI Prognostic Index, PNI Prognostic Nutritional Index, iPS inflammation-presepsin score, SOFA Sequential Organ Failure Assessment, qSOFA quick Sequential Organ Failure Assessment